Gene Regulatory Network

Homo Sapiens: liver_subnet_2

Gene Count Regulator Count Target Count Average Targets per TF Average TFs per Target
114 5 226 21.80 0.05

Top GO Annotations

monocarboxylic acid metabolic process (1.11e-51), protein activation cascade (4.34e-51), steroid metabolic process (8.55e-46), drug metabolic process (4.14e-45), bile acid and bile salt transport (2.92e-40), bile acid metabolic process (4.78e-33), response to xenobiotic stimulus (1.22e-26), serine family amino acid metabolic process (1.15e-23), cellular amino acid metabolic process (7.59e-20), triglyceride homeostasis (1.34e-19)

Tissue Types







GRN Members

TG TF Z-Score Correlation Tissue Type
ACMSD CUX2 4.22 0.98 endoderm
BBOX1 CUX2 4.12 0.97 endoderm
ACSM5 CUX2 4.15 0.97 endoderm
PLG CUX2 4.16 0.97 endoderm
HFE2 CUX2 4.13 0.97 endoderm
C3P1 CUX2 4.12 0.97 endoderm
HABP2 CUX2 4.12 0.97 endoderm
AFM CUX2 4.13 0.97 endoderm
DMGDH CUX2 4.16 0.97 endoderm
KNG1 CUX2 4.18 0.97 endoderm
ALDH8A1 CUX2 4.15 0.97 endoderm
DPYS CUX2 4.17 0.97 endoderm
BAAT CUX2 4.15 0.97 endoderm
HRG CUX2 4.15 0.97 endoderm
GLYAT CUX2 4.14 0.97 endoderm
ACSM2A CUX2 4.13 0.97 endoderm
UPB1 CUX2 4.15 0.97 endoderm
CYP4A22 CUX2 4.07 0.96 endoderm
RDH16 CUX2 4.07 0.96 endoderm
ANGPTL3 CUX2 4.11 0.96 endoderm
AFM LHX2 4.22 0.96 endoderm
AGXT2 CUX2 4.05 0.96 endoderm
ANXA10 CUX2 4.06 0.96 endoderm
CFHR2 CUX2 4.11 0.96 endoderm
CYP8B1 CUX2 4.10 0.96 endoderm
AMDHD1 CUX2 4.10 0.96 endoderm
ITIH4 CUX2 4.10 0.96 endoderm
LIPC CUX2 4.06 0.96 endoderm
AGXT CUX2 4.08 0.96 endoderm
SPP2 CUX2 4.07 0.96 endoderm
HAO2 CUX2 4.10 0.96 endoderm
APOC4 CUX2 4.08 0.96 endoderm
SLC22A1 LHX2 4.18 0.95 endoderm
HPR CUX2 4.05 0.95 endoderm
TM4SF4 CUX2 4.00 0.95 endoderm
F9 LHX2 4.16 0.95 endoderm
ACMSD LHX2 4.16 0.95 endoderm
DHTKD1 CUX2 4.02 0.95 endoderm
PLG LHX2 4.16 0.95 endoderm
APOF LHX2 4.14 0.95 endoderm
MASP1 CUX2 4.02 0.95 endoderm
CYP4A11 CUX2 4.01 0.95 endoderm
ANGPTL3 LHX2 4.16 0.95 endoderm
LECT2 LHX2 4.19 0.95 endoderm
BHMT2 CUX2 4.02 0.95 endoderm
SLC22A7 CUX2 4.03 0.95 endoderm
KNG1 LHX2 4.19 0.95 endoderm
C6 CUX2 4.02 0.95 endoderm
SLC2A2 CUX2 4.04 0.95 endoderm
LOC100506229 LHX2 4.17 0.95 endoderm
SLCO1B1 LHX2 4.16 0.95 endoderm
DPYS LHX2 4.15 0.95 endoderm
HAO1 LHX2 4.17 0.95 endoderm
GLYATL1 CUX2 4.03 0.95 endoderm
HRG LHX2 4.16 0.95 endoderm
CYP2A7 CUX2 4.01 0.95 endoderm
GLYAT LHX2 4.19 0.95 endoderm
F13B LHX2 4.18 0.95 endoderm
SPP2 LHX2 4.19 0.95 endoderm
C9 LHX2 4.13 0.95 endoderm
GYS2 LHX2 4.18 0.95 endoderm
SLC10A1 LHX2 4.13 0.95 endoderm
PON1 LHX2 4.20 0.95 endoderm
GC LHX2 4.16 0.95 endoderm
CYP2E1 LHX2 4.12 0.94 endoderm
APCS LHX2 4.09 0.94 endoderm
HAO2 LHX2 4.12 0.94 endoderm
APOC4 LHX2 4.08 0.94 endoderm
RTP3 LHX2 4.08 0.94 endoderm
CRHBP LHX2 4.08 0.94 endoderm
CYP4A22 LHX2 4.08 0.94 endoderm
MBL2 LHX2 4.09 0.94 endoderm
SLCO1B3 LHX2 4.11 0.94 endoderm
ACSM5 LHX2 4.08 0.94 endoderm
RDH16 LHX2 4.10 0.94 endoderm
HFE2 LHX2 4.13 0.94 endoderm
HPX LHX2 4.07 0.94 endoderm
C3P1 LHX2 4.09 0.94 endoderm
HABP2 LHX2 4.13 0.94 endoderm
DMGDH LHX2 4.11 0.94 endoderm
CFHR3 LHX2 4.06 0.94 endoderm
UGT2B4 LHX2 4.10 0.94 endoderm
CFHR2 LHX2 4.08 0.94 endoderm
ALDH8A1 LHX2 4.12 0.94 endoderm
LPA LHX2 4.07 0.94 endoderm
AKR1C4 LHX2 4.11 0.94 endoderm
BAAT LHX2 4.11 0.94 endoderm
ACOT12 LHX2 4.12 0.94 endoderm
CLDN14 LHX2 4.10 0.94 endoderm
OIT3 LHX2 4.10 0.94 endoderm
GLYATL1 LHX2 4.10 0.94 endoderm
ITIH1 LHX2 4.07 0.94 endoderm
GLS2 LHX2 4.09 0.94 endoderm
CYP2C9 LHX2 4.07 0.94 endoderm
GPLD1 LHX2 4.09 0.94 endoderm
AGXT LHX2 4.10 0.94 endoderm
C8A LHX2 4.08 0.94 endoderm
ADH1A LHX2 4.08 0.94 endoderm
ACSM2A LHX2 4.12 0.94 endoderm
AKR1D1 LHX2 4.11 0.94 endoderm
UPB1 LHX2 4.12 0.94 endoderm
CFHR4 LHX2 4.09 0.94 endoderm
LOC100507008 LHX2 4.08 0.94 endoderm
CYP2C8 LHX2 4.09 0.94 endoderm
BBOX1 LHX2 4.05 0.93 endoderm
ANGPTL6 LHX2 4.02 0.93 endoderm
THRSP LHX2 4.05 0.93 endoderm
MASP1 LHX2 4.01 0.93 endoderm
CYP4A11 LHX2 4.06 0.93 endoderm
AGXT2 LHX2 4.01 0.93 endoderm
SLC22A7 LHX2 4.06 0.93 endoderm
CYP8B1 LHX2 4.05 0.93 endoderm
SLC2A2 LHX2 4.04 0.93 endoderm
FCN2 LHX2 4.00 0.93 endoderm
CYP1A2 LHX2 4.04 0.93 endoderm
KLKB1 LHX2 4.06 0.93 endoderm
HOGA1 LHX2 4.01 0.93 endoderm
TRPM8 LHX2 4.04 0.93 endoderm
SERPINA4 LHX2 4.03 0.93 endoderm
ITIH4 LHX2 4.05 0.93 endoderm
CLEC1B LHX2 4.03 0.93 endoderm
CD5L LHX2 4.06 0.93 endoderm
VTN LHX2 4.00 0.93 endoderm
CPS1 LHX2 4.05 0.93 endoderm
LOC100507008 ZGPAT 4.19 0.92 endoderm
THRSP ZGPAT 4.06 0.91 endoderm
MASP1 ZGPAT 4.03 0.90 endoderm
SRD5A2 ZGPAT 4.00 0.90 endoderm
CYP2A7 ZGPAT 4.04 0.90 endoderm
TRPM8 RXRA 4.06 0.84 endoderm
CYP2C19 RXRA 4.05 0.83 endoderm
PFKFB1 RXRA 4.05 0.83 endoderm
AGXT2 RXRA 4.04 0.83 endoderm
LIPC RXRA 4.01 0.83 endoderm
PFKFB1 ATOH7 4.30 0.81 endoderm
AGXT2 ATOH7 4.15 0.79 endoderm
TRPM8 ATOH7 4.13 0.79 endoderm
LOC100422737 ATOH7 4.14 0.79 endoderm
AMDHD1 LHX2 4.46 0.79 germ_esc
ANXA10 ATOH7 4.05 0.78 endoderm
LPA ATOH7 4.12 0.78 endoderm
C22orf45 ATOH7 4.11 0.78 endoderm
ACSM2A ATOH7 4.12 0.78 endoderm
SLCO1B3 ATOH7 4.00 0.77 endoderm
CFHR3 ATOH7 4.05 0.77 endoderm
LIPC ATOH7 4.03 0.77 endoderm
GPLD1 ATOH7 4.01 0.77 endoderm
PON1 ATOH7 4.02 0.77 endoderm
SLC6A1 CUX2 8.86 0.72 all
UPB1 ZGPAT 10.20 0.71 all
SLC6A1 LHX2 5.87 0.68 all
AFM ZGPAT 8.89 0.67 all
AGXT2L1 CUX2 7.29 0.66 all
CYP4A11 ZGPAT 8.71 0.66 all
HAO2 ZGPAT 8.36 0.65 all
SLC22A7 ZGPAT 8.33 0.65 all
GPLD1 CUX2 6.80 0.64 all
LPA ZGPAT 7.90 0.63 all
CYP2E1 CUX2 6.65 0.63 all
CLDN14 ZGPAT 7.88 0.63 all
SLC22A1 ZGPAT 7.29 0.61 all
GNMT ZGPAT 7.29 0.61 all
GLS2 ZGPAT 7.23 0.61 all
AGXT2L1 LHX2 4.78 0.60 all
GLYAT ZGPAT 6.92 0.59 all
PON1 CUX2 5.79 0.59 all
LOC100507008 CUX2 5.74 0.59 all
GYS2 ZGPAT 6.65 0.58 all
AKR1D1 ZGPAT 6.62 0.58 all
HABP2 ZGPAT 6.62 0.58 all
ACSM5 ZGPAT 6.69 0.58 all
F9 CUX2 5.63 0.58 all
C9 CUX2 5.71 0.58 all
GYS2 CUX2 5.38 0.57 all
AKR1D1 CUX2 5.53 0.57 all
NAT8 ZGPAT 6.40 0.57 all
SLCO1B1 CUX2 5.49 0.57 all
KLKB1 CUX2 5.39 0.57 all
LECT2 ZGPAT 6.37 0.57 all
F13B CUX2 5.31 0.56 all
CFHR5 CUX2 5.32 0.56 all
CFHR3 CUX2 5.21 0.56 all
APOF CUX2 5.32 0.56 all
LOC100506229 ZGPAT 6.24 0.56 all
AKR1C4 CUX2 5.26 0.56 all
APOC4 ZGPAT 6.01 0.55 all
LPA CUX2 5.13 0.55 all
IDO2 ZGPAT 5.90 0.55 all
RTP3 ZGPAT 5.92 0.55 all
CYP2C8 CUX2 5.19 0.55 all
SLCO1B3 CUX2 5.10 0.55 all
OIT3 CUX2 5.11 0.55 all
MBL2 CUX2 5.07 0.55 all
LOC100506229 CUX2 5.10 0.55 all
CFHR4 CUX2 5.00 0.54 all
LECT2 CUX2 4.89 0.54 all
ITIH1 CUX2 4.98 0.54 all
HAO1 CUX2 4.86 0.53 all
C8A CUX2 4.74 0.53 all
LOC100507389 ZGPAT 5.62 0.53 all
ACOT12 CUX2 4.77 0.53 all
BAAT ZGPAT 5.38 0.52 all
APCS CUX2 4.65 0.52 all
CYP2C9 CUX2 4.50 0.51 all
CYP1A2 ZGPAT 5.13 0.51 all
GNMT CUX2 4.59 0.51 all
GC CUX2 4.44 0.50 all
SLC17A2 CUX2 4.43 0.50 all
SLC22A1 CUX2 4.34 0.50 all
LBP CUX2 4.31 0.49 all
GCDH ZGPAT 4.80 0.49 all
SPP2 ZGPAT 4.89 0.49 all
ADH1A CUX2 4.24 0.49 all
HPX CUX2 4.27 0.49 all
UGT2B4 CUX2 4.18 0.49 all
CYP2A6 ZGPAT 4.69 0.48 all
TRPM8 CUX2 4.10 0.48 all
C3P1 ZGPAT 4.78 0.48 all
FCN2 CUX2 4.17 0.48 all
BBOX1 ZGPAT 4.59 0.47 all
SLC10A1 CUX2 4.04 0.47 all
SLC10A1 ZGPAT 4.39 0.46 all
CD5L ZGPAT 4.16 0.44 all
FABP5 ATOH7 4.02 -0.77 endoderm
CLIC1 ATOH7 4.13 -0.79 endoderm