Gene Regulatory Network

Homo Sapiens: lung_subnet_4

Gene Count Regulator Count Target Count Average Targets per TF Average TFs per Target
143 10 262 13.60 0.07

Top GO Annotations

chemical homeostasis within a tissue (1.29e-28), ameboidal cell migration (5.06e-06), organ growth (1.6e-05), respiratory gaseous exchange (0.000217), cellular response to mechanical stimulus (0.00043), aminoglycan metabolic process (0.000574), muscle cell proliferation (0.00534), regulation of angiogenesis (0.0157), protein secretion (0.0213)

Tissue Types







GRN Members

TG TF Z-Score Correlation Tissue Type
BNIPL ZNF750 14.95 0.90 all
LMO3 ZNF750 5.50 0.85 endoderm
LRP2 ERBB4 4.43 0.84 endoderm
SFTPD ZNF750 5.30 0.84 endoderm
SFTPC ERBB4 4.24 0.82 endoderm
LOC286189 ZNF750 5.15 0.82 endoderm
SFTA2 ZNF750 5.06 0.82 endoderm
LOC286189 ERBB4 4.13 0.81 endoderm
SLCO3A1 FOXC1 4.68 0.81 endoderm
CX3CL1 GATA2 4.18 0.81 endoderm
SFTPB ERBB4 4.11 0.81 endoderm
SFTPA2 ZNF750 4.88 0.80 endoderm
PGC GATA2 4.11 0.80 endoderm
SUSD2 SOX18 4.41 0.80 endoderm
SFTA2 SOX18 4.36 0.80 endoderm
NAPSA ZNF750 4.87 0.80 endoderm
C20orf160 GATA2 4.04 0.79 endoderm
PGC SOX18 4.31 0.79 endoderm
CTSH SOX18 4.33 0.79 endoderm
SCN1A GATA2 4.04 0.79 endoderm
MUC15 ERBB4 4.00 0.79 endoderm
C8orf34 ZNF750 4.83 0.79 endoderm
SFTPD ERBB4 4.00 0.79 endoderm
ITGA10 GATA2 4.00 0.79 endoderm
CYP4B1 ZNF750 4.76 0.79 endoderm
SFTPD SOX18 4.33 0.79 endoderm
GKN2 SOX18 4.32 0.79 endoderm
CRTAC1 GATA2 4.01 0.79 endoderm
SFTPB ZNF750 4.67 0.78 endoderm
PEBP4 ZNF750 4.73 0.78 endoderm
RHOBTB2 SOX18 4.24 0.78 endoderm
SFTPC SOX18 4.26 0.78 endoderm
ROS1 ZNF750 4.71 0.78 endoderm
AGER SOX18 4.21 0.78 endoderm
CYP4B1 SOX18 4.20 0.78 endoderm
NAPSA SOX18 4.23 0.78 endoderm
SCGB3A1 ZNF750 4.69 0.78 endoderm
SFTPB SOX18 4.22 0.78 endoderm
ZBED2 ZNF750 4.73 0.78 endoderm
PDLIM2 SOX18 4.19 0.77 endoderm
C12orf68 RORB 5.20 0.77 all
AGER ZNF750 4.64 0.77 endoderm
PLA2G1B ZNF750 4.59 0.77 endoderm
CACNA2D2 ZNF750 4.58 0.77 endoderm
C19orf59 ZNF750 4.58 0.77 endoderm
PEBP4 SOX18 4.11 0.77 endoderm
ARHGEF26-AS1 ZNF750 4.48 0.76 endoderm
FMO2 FOXC1 4.27 0.76 endoderm
ABCA3 ZNF750 4.46 0.76 endoderm
RILPL2 FOXC1 4.27 0.76 endoderm
RILPL2 FOXC2 4.20 0.76 endoderm
SLC46A2 ZNF750 9.54 0.76 all
SLC26A9 ZNF750 4.52 0.76 endoderm
CHI3L2 SOX18 4.10 0.76 endoderm
CACNA2D2 SOX18 4.09 0.76 endoderm
CTSH ZNF750 4.48 0.76 endoderm
FAM46B SOX18 4.03 0.76 endoderm
PLA2G1B SOX18 4.02 0.76 endoderm
C19orf59 FOXC1 4.29 0.76 endoderm
SUSD2 ZNF750 4.45 0.76 endoderm
RTKN2 ZNF750 4.44 0.76 endoderm
LRRN4 ZNF750 4.45 0.76 endoderm
ACTN2 FOXC2 4.27 0.76 endoderm
FOXC2 FOXC1 4.16 0.75 endoderm
ARHGEF26-AS1 FOXC1 4.19 0.75 endoderm
CLEC5A ZNF750 4.36 0.75 endoderm
COL4A3 ZNF750 4.35 0.75 endoderm
FMO2 FOXC2 4.18 0.75 endoderm
RHOBTB2 ZNF750 4.40 0.75 endoderm
MAL FOXC1 4.16 0.75 endoderm
CXCL17 SOX18 4.01 0.75 endoderm
CXCL17 ZNF750 4.39 0.75 endoderm
RRAD FOXC2 4.13 0.75 endoderm
ELFN2 ZNF750 4.44 0.75 endoderm
OLR1 ZNF750 4.40 0.75 endoderm
TREM1 FOXC2 4.15 0.75 endoderm
TREM1 ZNF750 4.44 0.75 endoderm
SCN1A RORB 5.03 0.75 all
LOC100128840 ZNF750 4.38 0.75 endoderm
SCGB1A1 ZNF750 4.41 0.75 endoderm
HAS1 FOXC1 4.05 0.74 endoderm
FMO2 ZNF750 4.27 0.74 endoderm
CXCL17 FOXC2 4.02 0.74 endoderm
RRAD FOXC1 4.10 0.74 endoderm
SFTPC ZNF750 4.31 0.74 endoderm
ACOXL ZNF750 4.33 0.74 endoderm
NKD2 FOXC2 4.10 0.74 endoderm
TREM1 FOXC1 4.07 0.74 endoderm
ESYT3 ZNF750 9.01 0.74 all
NAPSA FOXC2 4.09 0.74 endoderm
SFTPD FOXC1 4.07 0.74 endoderm
HIGD1B FOXC2 4.10 0.74 endoderm
SLCO3A1 FOXC2 4.07 0.74 endoderm
ACTN2 FOXC1 4.05 0.74 endoderm
COL8A1 ZNF750 4.20 0.73 endoderm
SERTM1 ZNF750 4.21 0.73 endoderm
CHIA ZNF750 4.23 0.73 endoderm
MAL ZNF750 4.20 0.73 endoderm
ESAM SOX18 12.11 0.73 all
MUC15 ZNF750 8.87 0.73 all
LOC100507632 FOXC1 4.01 0.73 endoderm
LOC285043 ZNF750 4.24 0.73 endoderm
PHACTR1 ZNF750 4.24 0.73 endoderm
TSPAN6 ZC3H8 4.19 0.73 endoderm
ERBB4 RORB 5.09 0.73 endoderm
SLCO3A1 ZNF750 4.21 0.73 endoderm
GKN2 ZNF750 4.19 0.73 endoderm
CRTAC1 ZNF750 4.10 0.72 endoderm
USP44 ZNF750 4.09 0.72 endoderm
KLRG2 ZNF750 4.07 0.72 endoderm
ADAMTS8 ZNF750 4.11 0.72 endoderm
RILPL2 ZNF750 4.08 0.72 endoderm
TLR5 ZNF750 4.14 0.72 endoderm
VEPH1 ZNF750 4.09 0.72 endoderm
ST6GALNAC5 ZNF750 4.12 0.72 endoderm
LRP2 ZNF750 4.10 0.72 endoderm
LOC100128750 ZNF750 4.07 0.71 endoderm
PHACTR3 ZNF750 4.04 0.71 endoderm
IL27RA ZNF750 4.01 0.71 endoderm
LOC728196 ZNF750 4.06 0.71 endoderm
PCDP1 ZNF750 4.05 0.71 endoderm
LTBP2 ZNF750 4.00 0.71 endoderm
COQ3 ZC3H8 4.04 0.71 endoderm
RRAD ZNF750 4.06 0.71 endoderm
LOC100507632 ZNF750 4.06 0.71 endoderm
WWC3 ZNF750 4.05 0.71 endoderm
SLC6A4 ANKRD1 5.80 0.70 endoderm
TDRD9 RORB 4.70 0.70 endoderm
LOC286189 RORB 4.59 0.69 endoderm
BAALC OLIG1 4.92 0.69 all
GALNTL2 RORB 4.59 0.69 endoderm
ITGA10 RORB 4.62 0.69 endoderm
LRP2 RORB 4.47 0.68 endoderm
LOC153577 RORB 4.38 0.67 endoderm
SCN1A ERBB4 5.28 0.67 all
C19orf59 RORB 4.37 0.67 endoderm
CRTAC1 RORB 4.37 0.67 endoderm
SFTPA2 RORB 4.26 0.66 endoderm
LOC100507632 ANKRD1 5.18 0.66 endoderm
ACOT9 RORB 4.33 0.66 endoderm
GATA2 RORB 4.26 0.66 endoderm
SFTPD RORB 4.29 0.66 endoderm
RHOBTB2 RORB 4.19 0.65 endoderm
WDR69 RORB 4.19 0.65 endoderm
PHACTR1 RORB 4.17 0.65 endoderm
ST6GALNAC5 OLIG1 4.29 0.65 endoderm
CX3CL1 ANKRD1 5.10 0.65 endoderm
ABCA3 RORB 4.10 0.64 endoderm
CHI3L2 ANKRD1 4.92 0.64 endoderm
PCDHB4 OLIG1 4.21 0.64 endoderm
CYP2F1 RORB 4.05 0.64 endoderm
MUC15 ANKRD1 5.03 0.64 endoderm
PDE1C ANKRD1 6.78 0.64 all
PLA2G1B RORB 4.08 0.64 endoderm
SH3RF3-AS1 RORB 4.04 0.64 endoderm
SLCO3A1 RORB 4.06 0.64 endoderm
ZBED2 RORB 4.03 0.64 endoderm
CNTN6 OLIG1 4.23 0.64 endoderm
RNF182 OLIG1 4.14 0.63 endoderm
KLRG2 ANKRD1 4.83 0.63 endoderm
GKN2 RORB 4.02 0.63 endoderm
ARHGEF26-AS1 OLIG1 4.27 0.63 all
COL6A5 ANKRD1 4.67 0.62 endoderm
RILPL2 ANKRD1 4.75 0.62 endoderm
ZNF365 ANKRD1 4.74 0.62 endoderm
CTSH ANKRD1 4.68 0.62 endoderm
LOC285043 OLIG1 4.07 0.62 endoderm
C19orf59 ANKRD1 4.65 0.62 endoderm
LOC100506725 ANKRD1 4.66 0.62 endoderm
LOC100128750 ANKRD1 4.54 0.61 endoderm
KIAA0408 OLIG1 4.11 0.61 all
TREM1 ANKRD1 4.57 0.61 endoderm
SCN1A ANKRD1 4.55 0.61 endoderm
AGER ANKRD1 4.54 0.61 endoderm
CYP4B1 ANKRD1 4.53 0.61 endoderm
EMR3 ANKRD1 4.53 0.61 endoderm
CLEC5A ANKRD1 4.46 0.60 endoderm
GKN2 ANKRD1 4.43 0.60 endoderm
SERTM1 ANKRD1 4.45 0.60 endoderm
SLC22A15 ANKRD1 4.44 0.60 endoderm
GATA2 ANKRD1 4.43 0.60 endoderm
SUSD2 ANKRD1 4.41 0.60 endoderm
SFTPD ANKRD1 4.49 0.60 endoderm
NAPSA ANKRD1 4.42 0.60 endoderm
HCAR3 ANKRD1 4.50 0.60 endoderm
FGFBP2 ANKRD1 4.38 0.59 endoderm
FMO2 ANKRD1 4.38 0.59 endoderm
LOC286189 ANKRD1 4.32 0.59 endoderm
MAL ANKRD1 4.34 0.59 endoderm
OLR1 ANKRD1 4.36 0.59 endoderm
PHACTR1 ANKRD1 4.29 0.59 endoderm
ST6GALNAC5 ANKRD1 4.33 0.59 endoderm
C4orf47 ERBB4 4.28 0.59 all
BDNF ANKRD1 4.34 0.59 endoderm
CRTAC1 ANKRD1 4.29 0.59 endoderm
PEBP4 ANKRD1 4.30 0.59 endoderm
LRRN4 ANKRD1 4.37 0.59 endoderm
ARHGEF26-AS1 ANKRD1 4.33 0.59 endoderm
RNF182 ANKRD1 4.19 0.58 endoderm
SLC24A4 ANKRD1 4.23 0.58 endoderm
WARS ANKRD1 4.20 0.58 endoderm
PGC ANKRD1 4.25 0.58 endoderm
LEFTY2 ANKRD1 4.20 0.58 endoderm
PLA2G1B ANKRD1 4.16 0.58 endoderm
ESM1 ANKRD1 4.26 0.58 endoderm
LINC00551 ANKRD1 4.27 0.58 endoderm
ZBED2 ANKRD1 4.20 0.58 endoderm
SCN4B ANKRD1 4.18 0.58 endoderm
RTKN2 ANKRD1 4.18 0.58 endoderm
SLC46A2 ANKRD1 4.20 0.58 endoderm
SFTPA2 ANKRD1 4.08 0.57 endoderm
BAALC ANKRD1 4.10 0.57 endoderm
LOC254057 ANKRD1 4.09 0.57 endoderm
SFTA2 ANKRD1 4.06 0.57 endoderm
MGARP ANKRD1 4.10 0.57 endoderm
SPOCK2 ANKRD1 4.11 0.57 endoderm
SEMA3G ANKRD1 4.15 0.57 endoderm
HIGD1B ANKRD1 4.14 0.57 endoderm
S100A3 ANKRD1 4.91 0.57 germ_esc
IL27RA ANKRD1 4.00 0.56 endoderm
SFTPC ANKRD1 4.04 0.56 endoderm
ADAMTS8 ANKRD1 4.04 0.56 endoderm
TACSTD2 ZNF750 5.27 0.56 all
HOPX ZNF750 4.95 0.54 all
ACTN2 ANKRD1 4.94 0.54 all
VEPH1 SOX18 5.96 0.53 all
LTBP2 SOX18 5.66 0.52 all
COL6A5 ZNF750 4.49 0.51 all
COL8A1 SOX18 5.27 0.49 all
SH2D3C SOX18 5.15 0.49 all
FAM46B ZNF750 4.20 0.49 all
TACSTD2 FOXC1 4.12 0.49 all
LOC285043 ANKRD1 4.03 0.48 all
HIST1H2BD ANKRD1 4.15 -0.57 endoderm
SCG5 ANKRD1 4.47 -0.60 endoderm
MRPL1 RORB 4.00 -0.63 endoderm
ATP5I RORB 4.27 -0.66 endoderm
UQCRQ RORB 4.26 -0.66 endoderm
CD300C ZC3H8 4.00 -0.71 endoderm
HIST1H2BD RORB 4.81 -0.71 endoderm
SCGB3A1 ZC3H8 4.01 -0.71 endoderm
TSPAN4 ZC3H8 4.03 -0.71 endoderm
ABCA3 ZC3H8 4.05 -0.72 endoderm
CACNA2D2 ZC3H8 4.10 -0.72 endoderm
SFTA2 ZC3H8 4.10 -0.72 endoderm
CENPV ZNF750 4.17 -0.73 endoderm
NKD2 ZC3H8 4.14 -0.73 endoderm
PLOD2 ZNF750 4.20 -0.73 endoderm
CYP4B1 ZC3H8 4.13 -0.73 endoderm
ALDH3B1 ZC3H8 4.15 -0.73 endoderm
HN1L FOXC2 4.08 -0.74 endoderm
ATP5G3 FOXC1 4.11 -0.74 endoderm
TACSTD2 ZC3H8 4.27 -0.74 endoderm
SUSD2 ZC3H8 4.29 -0.74 endoderm
PEBP4 ZC3H8 4.23 -0.74 endoderm
TSPAN6 ZNF750 4.37 -0.75 endoderm
EPB41L4B SOX18 4.05 -0.76 endoderm
SH2D3C ZC3H8 4.44 -0.76 endoderm
SFXN4 SOX18 4.11 -0.77 endoderm
ATP5I ERBB4 4.01 -0.79 endoderm
HIST1H2BD GATA2 4.04 -0.79 endoderm
HIST1H2BD ERBB4 4.07 -0.80 endoderm