Gene Regulatory Network

Homo Sapiens: lung_subnet_5

Gene Count Regulator Count Target Count Average Targets per TF Average TFs per Target
68 9 187 7.00 0.14

Top GO Annotations

regulation of cell morphogenesis (9.53e-06), tube development (5.39e-05), respiratory system development (8.99e-05), limb development (0.00256), negative regulation of locomotion (0.0091)

Tissue Types







GRN Members

TG TF Z-Score Correlation Tissue Type
SFTA3 NKX2-1 51.53 0.95 all
TMEM108 TBX5 4.67 0.94 endoderm
IGSF10 PKNOX2 4.15 0.93 endoderm
CRNDE NKX2-1 4.23 0.93 endoderm
KAL1 NKX2-1 4.19 0.93 endoderm
GDF10 TBX5 4.60 0.93 endoderm
IRX5 NKX2-1 4.12 0.92 endoderm
KCNK3 PKNOX2 4.08 0.92 endoderm
TMEM108 NKX2-1 4.11 0.92 endoderm
WIF1 TBX5 4.43 0.91 endoderm
EGFL6 TBX5 4.36 0.91 endoderm
C1orf198 PKNOX2 4.01 0.91 endoderm
SCGB3A2 TBX5 4.37 0.91 endoderm
CLDN18 NKX2-1 43.44 0.91 all
SFTA3 TBX5 4.39 0.91 endoderm
IRX3 NKX2-1 4.02 0.90 endoderm
TRPC6 TBX5 4.29 0.90 endoderm
SMTNL2 TBX5 4.31 0.90 endoderm
IRX5 TBX2 4.45 0.90 endoderm
KCNK3 TBX5 4.30 0.90 endoderm
NKX2-1 ETV1 4.50 0.90 endoderm
IRX2 TBX2 4.34 0.89 endoderm
PLEKHH2 TBX5 4.28 0.89 endoderm
CLDN18 ETV1 4.40 0.89 endoderm
IRX2 TBX5 4.26 0.89 endoderm
TMEM108 TBX2 4.34 0.89 endoderm
CHN1 TBX5 4.20 0.88 endoderm
AQP4 ETV1 4.31 0.88 endoderm
NTNG1 TBX5 4.17 0.88 endoderm
WIF1 ETV1 4.35 0.88 endoderm
ARAP3 TBX2 4.27 0.88 endoderm
SFTA3 ETV1 4.33 0.88 endoderm
IRX5 TBX4 4.60 0.88 endoderm
GDF10 ETV1 4.36 0.88 endoderm
WIF1 TBX2 4.33 0.88 endoderm
KAL1 TBX5 4.19 0.88 endoderm
EGFL6 TBX2 4.26 0.88 endoderm
TMEM108 TBX4 4.63 0.88 endoderm
PLEKHH2 TBX4 4.52 0.87 endoderm
SLIT2 ETV1 4.29 0.87 endoderm
SLIT2 TBX5 4.10 0.87 endoderm
IRX2 ETV1 4.25 0.87 endoderm
GJA5 TBX5 4.07 0.87 endoderm
KAL1 TBX2 4.22 0.87 endoderm
TRPC6 ETV1 4.15 0.86 endoderm
CORO2B TBX5 4.03 0.86 endoderm
CLEC14A TBX2 4.11 0.86 endoderm
GRIA1 TBX5 4.04 0.86 endoderm
LPL ETV1 4.18 0.86 endoderm
ELF5 TBX5 4.01 0.86 endoderm
TBX5-AS1 ETV1 4.14 0.86 endoderm
KCNJ15 ETV1 4.17 0.86 endoderm
ALDH1A2 TBX5 4.01 0.86 endoderm
KIAA1462 ETV1 4.09 0.85 endoderm
TRPC6 TBX4 4.38 0.85 endoderm
PLEKHH2 ETV1 4.11 0.85 endoderm
MEGF6 TBX2 4.04 0.85 endoderm
NTNG1 TBX2 4.08 0.85 endoderm
GJA5 ETV1 4.07 0.85 endoderm
FIGF ETV1 4.12 0.85 endoderm
SLC34A2 ETV1 4.08 0.85 endoderm
CRNDE TBX2 4.07 0.85 endoderm
KCNK3 ETV1 4.13 0.85 endoderm
ALDH1A2 TBX4 4.35 0.85 endoderm
TMEM108 ETV1 4.11 0.85 endoderm
KAL1 ETV1 4.09 0.85 endoderm
WIF1 TBX4 4.35 0.85 endoderm
RHOJ ETV1 4.01 0.84 endoderm
ELF5 ETV1 4.04 0.84 endoderm
IRX2 TBX4 4.25 0.84 endoderm
PDPN ETV1 4.01 0.84 endoderm
CRNDE ETV1 4.01 0.84 endoderm
IRX5 ETV1 4.04 0.84 endoderm
EGFL6 TBX4 4.19 0.83 endoderm
NTNG1 TBX4 4.22 0.83 endoderm
ELF5 TBX4 4.15 0.82 endoderm
TBX5-AS1 TBX5 12.36 0.81 all
SMTNL2 TBX4 4.02 0.81 endoderm
H3F3B TBX4 4.01 0.81 endoderm
CHN1 HOXC6 4.37 0.79 endoderm
C16orf89 NFIX 4.31 0.77 endoderm
FAM189A2 NFIX 4.28 0.77 endoderm
EGFL6 HOXC6 4.15 0.77 endoderm
SCGB3A2 NFIX 4.24 0.76 endoderm
TMEM108 HOXC6 4.12 0.76 endoderm
SFTA3 NFIX 4.23 0.76 endoderm
EGFL6 NFIX 4.17 0.76 endoderm
NKX2-1 NFIX 4.21 0.76 endoderm
KIAA1462 NFIX 4.14 0.75 endoderm
SCGB3A2 NKX2-1 22.25 0.75 all
TBX5 HOXC6 4.03 0.75 endoderm
FIGF NFIX 4.10 0.75 endoderm
SLC34A2 NFIX 4.15 0.75 endoderm
RAB38 HOXC6 4.04 0.75 endoderm
TMEM108 NFIX 4.11 0.75 endoderm
WIF1 NFIX 4.15 0.75 endoderm
CLEC14A NFIX 4.05 0.74 endoderm
PTRF NFIX 4.03 0.74 endoderm
SLC34A2 NKX2-1 21.60 0.74 all
AQP4 NFIX 4.05 0.74 endoderm
GJA5 NFIX 4.02 0.74 endoderm
KCNK3 NFIX 4.05 0.74 endoderm
CHST12 NFIX 4.04 0.74 endoderm
SGCG NFIX 4.04 0.74 endoderm
GDF10 NKX2-1 21.56 0.74 all
GDF10 NFIX 4.02 0.74 endoderm
HSPA12B NFIX 4.06 0.74 endoderm
KCNK3 NKX2-1 18.98 0.71 all
A1CF FOXA3 8.54 0.70 all
C16orf89 NKX2-1 15.95 0.67 all
WIF1 NKX2-1 14.56 0.65 all
MOGAT2 FOXA3 7.09 0.64 all
TBX2 NKX2-1 13.69 0.64 all
C1orf198 NFIX 4.79 0.63 all
HSD17B2 FOXA3 6.99 0.63 all
SFTA3 TBX2 8.94 0.61 all
TBX5-AS1 TBX2 8.92 0.61 all
SGCG TBX5 6.07 0.59 all
IRX5 TBX5 6.16 0.59 all
EGFL6 NKX2-1 11.41 0.59 all
TRPC6 NKX2-1 10.91 0.58 all
NDNF NKX2-1 10.96 0.58 all
SLC34A2 TBX2 7.70 0.57 all
AQP4 NKX2-1 10.31 0.57 all
TBX5-AS1 NKX2-1 10.50 0.57 all
B3GALNT1 ETV1 4.90 0.56 all
SLC35D1 FOXA3 5.17 0.54 all
NKX2-1 TBX4 6.77 0.54 all
TBX5 ETV1 4.64 0.54 all
SCGB3A2 ETV1 4.26 0.52 all
LPL TBX5 4.62 0.51 all
SFTA3 TBX4 5.98 0.51 all
KCNK3 TBX4 5.67 0.50 all
IRX3 TBX5 4.50 0.50 all
TBX2 TBX4 5.80 0.50 all
TBX5 TBX2 5.72 0.49 all
C2orf72 FOXA3 4.40 0.49 all
GDF10 TBX2 5.46 0.48 all
GDF10 TBX4 5.07 0.47 all
KCNK3 TBX2 4.96 0.45 all
TBX5 TBX4 4.58 0.44 all
SCGB3A2 TBX4 4.40 0.43 all
HSPA12B TBX2 4.55 0.43 all
TBX5-AS1 TBX4 4.39 0.43 all
SLIT2 TBX2 4.44 0.42 all
SGCG TBX4 4.05 0.41 all
SLIT2 NKX2-1 5.34 0.41 all
SCGB3A2 TBX2 4.25 0.41 all
TBX5 NKX2-1 5.22 0.41 all
FAM189A2 NKX2-1 4.58 0.38 all
IRX2 NKX2-1 4.33 0.37 all
KCNJ15 NKX2-1 4.34 0.37 all
LPL NKX2-1 4.06 0.35 all
SGK2 NFIX 4.01 -0.74 endoderm
FOXA3 NFIX 4.07 -0.74 endoderm
A1CF NFIX 4.08 -0.74 endoderm
SLC35D1 NFIX 4.09 -0.75 endoderm
HSD17B2 NFIX 4.11 -0.75 endoderm
HINT1 NFIX 4.10 -0.75 endoderm
TPMT HOXC6 4.00 -0.75 endoderm
HSD17B2 TBX4 4.07 -0.81 endoderm
FABP1 ETV1 4.02 -0.84 endoderm
CYP2J2 ETV1 4.00 -0.84 endoderm
SLC35D1 ETV1 4.12 -0.85 endoderm
HSD17B2 ETV1 4.18 -0.86 endoderm
HSD17B2 TBX2 4.15 -0.86 endoderm
FABP1 TBX2 4.13 -0.86 endoderm
CYP2J2 TBX5 4.02 -0.86 endoderm
HSD17B2 TBX5 4.22 -0.89 endoderm
SGK2 NKX2-1 4.00 -0.90 endoderm
GRTP1 NKX2-1 4.02 -0.90 endoderm
MOGAT2 NKX2-1 4.01 -0.90 endoderm
A1CF NKX2-1 4.07 -0.91 endoderm
CYP2J2 NKX2-1 4.03 -0.91 endoderm
C16orf89 FOXA3 4.03 -0.92 endoderm
TRPC6 FOXA3 4.01 -0.92 endoderm
FABP1 NKX2-1 4.16 -0.92 endoderm
SLC34A2 FOXA3 4.01 -0.92 endoderm
SLC35D1 NKX2-1 4.22 -0.93 endoderm
LPL FOXA3 4.07 -0.93 endoderm
FABP1 PKNOX2 4.18 -0.93 endoderm
SCGB3A2 FOXA3 4.08 -0.93 endoderm
WIF1 FOXA3 4.19 -0.94 endoderm
NKX2-1 FOXA3 4.14 -0.94 endoderm
HSD17B2 NKX2-1 4.35 -0.95 endoderm
SFTA3 FOXA3 4.21 -0.95 endoderm