Gene Regulatory Network

Mus Musculus: fibroblast_subnet_5

Gene Count Regulator Count Target Count Average Targets per TF Average TFs per Target
106 46 10,449 9.18 0.11

Top GO Annotations

interleukin-6 production (1.5e-16), tumor necrosis factor superfamily cytokine production (2.4e-15), inflammatory response (2.74e-15), I-kappaB kinase/NF-kappaB cascade (1.75e-14), lipopolysaccharide-mediated signaling pathway (5e-12)

Tissue Types







GRN Members

TG TF Z-Score Correlation Tissue Type
Rgs19 Twist1 4.05 0.86 non-blood
Asns Twist1 4.10 0.86 non-blood
Chst12 Twist1 4.01 0.85 non-blood
Mapt Esrrg 4.31 0.84 non-blood
S100a6 Jdp2 4.42 0.83 non-blood
Sirt3 Esrrg 4.26 0.83 non-blood
Ankrd33b Esrrg 4.24 0.83 non-blood
Erbb3 Esrrg 4.05 0.81 non-blood
Vgll3 Jdp2 4.31 0.81 non-blood
As3mt Esrrg 4.01 0.80 non-blood
Alpl Esrrg 4.01 0.80 non-blood
Asns Jdp2 4.07 0.79 non-blood
Twist1 Jdp2 4.01 0.78 non-blood
Nfkbiz Tnfaip3 7.27 0.78 all
Twist1 Twist2 10.19 0.77 all
Akr1b8 Ifi204 4.33 0.76 ectoderm
Ccl2 Relb 4.91 0.74 non-blood
Ccl7 Relb 4.82 0.74 non-blood
Zc3h12a Relb 7.59 0.72 all
Relb Tnfaip3 6.13 0.72 all
Mob3a Relb 4.69 0.72 non-blood
Ikbke Tnfaip3 6.07 0.71 all
Nfkbie Tnfaip3 6.08 0.71 all
Mmp3 Lhx8 9.56 0.71 non-blood
Chst12 Relb 4.56 0.71 non-blood
Rgs19 Relb 4.40 0.70 non-blood
Ltbp2 Relb 4.40 0.70 non-blood
S100a6 Tnfaip3 4.40 0.70 endoderm
S100a4 Relb 4.45 0.70 non-blood
S100a6 Relb 4.44 0.70 non-blood
Lgals1 Relb 4.47 0.70 non-blood
Vgll3 Relb 4.45 0.70 non-blood
Arsa Relb 4.28 0.69 non-blood
Micall2 Relb 4.30 0.69 non-blood
Twist1 Relb 4.36 0.69 non-blood
Ccl2 Bcl3 7.07 0.69 non-blood
Twist2 Relb 4.32 0.69 non-blood
Vgll3 Ifi204 4.59 0.69 non-blood
Ccl7 Bcl3 7.06 0.69 non-blood
Vat1 Relb 4.33 0.69 non-blood
Tmem173 Relb 4.25 0.68 non-blood
Plcb3 Tfe3 4.51 0.68 non-blood
Vgll3 Egr2 4.43 0.68 non-blood
Rgs19 Ifi204 4.47 0.68 non-blood
Stambpl1 Relb 4.24 0.68 non-blood
Akr1b8 Relb 4.13 0.67 non-blood
Crlf2 Relb 4.15 0.67 non-blood
Ddr2 Relb 4.16 0.67 non-blood
Inf2 Relb 4.18 0.67 non-blood
Ahnak2 Relb 4.16 0.67 non-blood
Stambpl1 Tfe3 4.31 0.66 non-blood
Esyt2 Egr2 4.19 0.66 non-blood
Relb Bcl3 5.95 0.66 all
Twist2 Tfe3 4.24 0.66 non-blood
Dse Egr2 4.24 0.66 non-blood
Vgll3 Tnfaip3 4.68 0.66 non-blood
S100a6 Ifi204 4.19 0.65 non-blood
Matn2 Ifi204 4.16 0.65 non-blood
Ust Ifi204 4.18 0.65 non-blood
Arsa Tfe3 4.11 0.65 non-blood
Zc3h12a Bcl3 5.79 0.65 all
Arpc1b Tfe3 4.16 0.65 non-blood
Ccl2 Tnfaip3 4.56 0.65 non-blood
Mmp3 Bcl3 6.26 0.65 non-blood
F3 Ifi204 4.23 0.65 non-blood
Zcchc6 Ifi204 4.20 0.65 non-blood
Dse Tnfaip3 4.57 0.65 non-blood
Arsa Ifi204 4.19 0.65 non-blood
Esyt2 Ifi204 4.05 0.64 non-blood
Trappc4 Tfe3 4.05 0.64 non-blood
Lgals1 Tnfaip3 4.44 0.64 non-blood
Atp10a Egr2 4.00 0.64 non-blood
Gng10 Ifi204 4.04 0.64 non-blood
Anxa2 Ifi204 4.12 0.64 non-blood
Chst12 Tnfaip3 4.49 0.64 non-blood
Tlr2 Bcl3 6.08 0.64 non-blood
Vcam1 Bcl3 5.98 0.63 non-blood
Serpina3g Bcl3 6.05 0.63 non-blood
Dok1 Tnfaip3 4.39 0.63 non-blood
S100a4 Tnfaip3 4.23 0.62 non-blood
Slc47a1 Esrrg 4.67 0.62 all
Mob3a Tnfaip3 4.21 0.62 non-blood
Ccl7 Tnfaip3 4.25 0.62 non-blood
Twist1 Tnfaip3 4.15 0.61 non-blood
Adm Bcl3 5.62 0.61 non-blood
Ccl2 Lhx8 6.83 0.61 non-blood
Arpc1b Relb 5.49 0.61 all
Ccl7 Lhx8 6.78 0.61 non-blood
Ikbke Bcl3 4.98 0.60 all
Rgs19 Tnfaip3 4.02 0.60 non-blood
Ltbp2 Tnfaip3 4.08 0.60 non-blood
Maoa Tnfaip3 4.08 0.60 non-blood
Mlkl Tnfaip3 4.02 0.60 non-blood
Eno2 Bcl3 5.45 0.60 non-blood
Arhgdib Bcl3 5.37 0.60 non-blood
Car14 Esrrg 4.37 0.60 all
Vat1 Tnfaip3 4.03 0.60 non-blood
S100a4 Ifi204 7.63 0.60 all
Myd88 Bcl3 4.79 0.59 all
Clmp Twist1 6.34 0.59 all
Micall2 Bcl3 5.08 0.58 non-blood
Arsa Bcl3 5.08 0.58 non-blood
Shisa5 Bcl3 5.08 0.58 non-blood
Saa3 Bcl3 5.05 0.57 non-blood
Akr1b8 Bcl3 5.03 0.57 non-blood
F3 Bcl3 4.92 0.57 non-blood
Gba Bcl3 4.91 0.57 non-blood
Lgals1 Twist1 5.73 0.56 all
Dok1 Relb 4.66 0.56 all
S100a4 Jdp2 7.17 0.55 all
Ltbp2 Bcl3 4.72 0.55 non-blood
Cxcl3 Bcl3 4.74 0.55 non-blood
Saa3 Lhx8 5.58 0.55 non-blood
Mlkl Bcl3 4.67 0.55 non-blood
Tnfaip3 Bcl3 4.27 0.55 all
Cxcl10 Bcl3 4.62 0.55 non-blood
Nfkbiz Bcl3 4.35 0.55 all
Dse Ifi204 6.46 0.55 all
Mlkl Ifi204 6.24 0.54 all
Nfkbie Bcl3 4.17 0.54 all
Adamts4 Bcl3 4.59 0.54 non-blood
Bcl3 Lhx8 5.32 0.54 non-blood
Adora2b Bcl3 4.49 0.54 non-blood
Ikbke Lhx8 5.30 0.54 non-blood
Sbno2 Bcl3 4.16 0.54 all
Ly96 Bcl3 4.52 0.54 non-blood
Stambpl1 Bcl3 4.50 0.54 non-blood
Mob3a Bcl3 4.35 0.53 non-blood
B4galnt1 Bcl3 4.09 0.53 all
Relb Lhx8 5.15 0.53 non-blood
Ripk3 Bcl3 4.46 0.53 non-blood
Ripk3 Relb 4.32 0.53 all
Crlf2 Bcl3 4.27 0.52 non-blood
Cstb Bcl3 4.27 0.52 non-blood
Hgf Bcl3 4.23 0.52 non-blood
Rgs16 Bcl3 4.30 0.52 non-blood
Rgs16 Lhx8 4.93 0.52 non-blood
Ripk3 Lhx8 5.07 0.52 non-blood
Gzme Bcl3 4.33 0.52 non-blood
Ahnak2 Bcl3 4.24 0.52 non-blood
Tmem173 Bcl3 4.31 0.52 non-blood
B4galnt1 Lhx8 4.76 0.51 non-blood
Dok1 Bcl3 4.16 0.51 non-blood
Nfkbie Lhx8 4.80 0.51 non-blood
Serpina3g Lhx8 4.81 0.51 non-blood
Ccdc109b Bcl3 4.11 0.51 non-blood
Adora2b Lhx8 4.90 0.51 non-blood
Slc35a2 Bcl3 4.12 0.51 non-blood
Ggcx Bcl3 4.14 0.51 non-blood
Gzme Lhx8 4.86 0.51 non-blood
Micall2 Lhx8 4.64 0.50 non-blood
Csgalnact1 Bcl3 4.01 0.50 non-blood
Arhgdib Lhx8 4.64 0.50 non-blood
Serpinb2 Bcl3 4.03 0.50 non-blood
Ahnak2 Lhx8 4.75 0.50 non-blood
Rgs19 Bcl3 4.02 0.50 non-blood
Stambpl1 Lhx8 4.62 0.50 non-blood
S100a6 Bcl3 4.08 0.50 non-blood
Traf3ip2 Lhx8 4.50 0.49 non-blood
Pml Lhx8 4.56 0.49 non-blood
Mob3a Lhx8 4.49 0.49 non-blood
Akr1b8 Lhx8 4.47 0.49 non-blood
Sbno2 Lhx8 4.47 0.49 non-blood
Gba Lhx8 4.39 0.48 non-blood
Ltbp2 Lhx8 4.36 0.48 non-blood
Ccdc109b Lhx8 4.44 0.48 non-blood
Fam38a Lhx8 4.38 0.48 non-blood
Zc3h12a Lhx8 4.37 0.48 non-blood
Chst12 Lhx8 4.31 0.48 non-blood
Akr1b8 Tfe3 5.96 0.48 all
Nfkbiz Lhx8 4.30 0.48 non-blood
Ctsk Lhx8 4.34 0.48 non-blood
Tlr2 Lhx8 4.24 0.47 non-blood
Rgs19 Lhx8 4.18 0.47 non-blood
S100a6 Lhx8 4.21 0.47 non-blood
Cxcl3 Lhx8 4.20 0.47 non-blood
Dok1 Lhx8 4.27 0.47 non-blood
Vcam1 Lhx8 4.29 0.47 non-blood
Tcirg1 Lhx8 4.28 0.47 non-blood
Tnip1 Lhx8 4.19 0.47 non-blood
Tmem173 Lhx8 4.28 0.47 non-blood
S100a4 Lhx8 4.04 0.46 non-blood
Trappc4 Lhx8 4.08 0.46 non-blood
Lgals1 Lhx8 4.09 0.46 non-blood
Gpnmb Lhx8 4.14 0.46 non-blood
Adamts4 Lhx8 4.15 0.46 non-blood
Adm Lhx8 4.11 0.46 non-blood
Mob3a Egr2 4.28 0.46 all
Hexa Lhx8 4.05 0.46 non-blood
Inf2 Lhx8 4.11 0.46 non-blood
Vgll3 Lhx8 4.05 0.46 non-blood
Tnfaip3 Lhx8 4.06 0.46 non-blood
Gng10 Lhx8 4.04 0.46 non-blood
Inf2 Jdp2 4.92 0.45 all
Casp12 Ifi204 4.56 0.44 endoderm
Lgals1 Jdp2 4.75 0.44 all
Dse Jdp2 4.82 0.44 all
Lgals1 Ifi204 4.23 0.43 all
Ifi202b Ifi204 4.25 0.43 all
Vat1 Jdp2 4.59 0.43 all
Ikbke Ifi204 4.05 0.42 all
Rpl39l Lhx8 5.74 0.41 all
Mrpl50 Lhx8 4.00 -0.45 non-blood
Rab2a Lhx8 4.02 -0.46 non-blood
Atp5g3 Lhx8 4.07 -0.46 non-blood
Slc47a1 Lhx8 4.13 -0.46 non-blood
Atp5g3 Bcl3 4.06 -0.50 non-blood
Clcn3 Twist2 4.91 -0.53 all
Fn3k Tnfaip3 4.00 -0.60 non-blood
Atp5g3 Tnfaip3 4.00 -0.60 non-blood
Sirt3 Tnfaip3 4.09 -0.60 non-blood
Esrrg Tnfaip3 4.13 -0.61 non-blood
Mapt Tnfaip3 4.20 -0.61 non-blood
Alpl Ifi204 4.03 -0.63 non-blood
Ankrd33b Tfe3 4.03 -0.64 non-blood
BC030308 Tfe3 4.03 -0.64 non-blood
Slc47a1 Tnfaip3 4.53 -0.64 non-blood
Car14 Tnfaip3 4.64 -0.65 non-blood
Rap1gap Ifi204 4.17 -0.65 non-blood
Car14 Ifi204 4.30 -0.66 non-blood
As3mt Tfe3 4.33 -0.67 non-blood
Slc47a1 Ifi204 4.44 -0.67 non-blood
Car14 Relb 4.23 -0.68 non-blood
Mrpl50 Relb 4.21 -0.68 non-blood
Esrrg Relb 4.23 -0.68 non-blood
Clcn3 Relb 4.28 -0.68 non-blood
Erbb3 Relb 4.28 -0.68 non-blood
Erbb3 Ifi204 4.69 -0.70 non-blood
Slc47a1 Relb 4.65 -0.72 non-blood
Slc47a1 Jdp2 4.06 -0.78 non-blood
Sirt3 Jdp2 4.06 -0.78 non-blood
S100a4 Esrrg 4.04 -0.81 non-blood
Clmp Esrrg 4.08 -0.81 non-blood
Chst12 Esrrg 4.10 -0.81 non-blood
Asns Esrrg 4.14 -0.82 non-blood
Lgals1 Esrrg 4.40 -0.85 non-blood
As3mt Twist2 4.01 -0.85 non-blood
Sirt3 Twist1 4.01 -0.85 non-blood
Car14 Twist1 4.17 -0.87 non-blood
Ankrd33b Twist1 4.21 -0.88 non-blood
Mapt Twist1 4.19 -0.88 non-blood
Twist1 Esrrg 4.80 -0.90 non-blood
Slc47a1 Twist1 4.64 -0.93 non-blood