Gene Regulatory Network

Mus Musculus: skin_subnet_4

Gene Count Regulator Count Target Count Average Targets per TF Average TFs per Target
64 35 3,333 20.67 0.05

Top GO Annotations

negative regulation of immune system process (4.56e-25), negative regulation of immune response (1.65e-21), negative regulation of T cell activation (3.65e-19), innate immune response (7.76e-17), antigen processing and presentation (8.5e-15)

Tissue Types







GRN Members

TG TF Z-Score Correlation Tissue Type
H2-Aa Esr1 4.32 0.87 ectoderm
H2-Ab1 Esr1 4.07 0.84 ectoderm
Cd55 Esr1 4.04 0.83 ectoderm
Defb6 Esr1 4.00 0.83 ectoderm
Klrd1 Irf4 5.47 0.75 ectoderm
Ear2 Irf4 5.18 0.73 ectoderm
Cd207 Irf4 5.04 0.72 ectoderm
H2-Ob Ciita 9.46 0.72 all
Cysltr1 Irf4 4.91 0.71 ectoderm
Il18r1 Irf4 4.85 0.71 ectoderm
Ear3 Ciita 6.47 0.71 ectoderm
Nkg7 Irf4 4.74 0.70 ectoderm
Alox12e Irf4 4.73 0.70 ectoderm
Cd209e Ciita 6.28 0.70 ectoderm
Tcra Ciita 6.33 0.70 ectoderm
Cd3d Ciita 6.18 0.69 ectoderm
Cd209f Irf4 4.58 0.68 ectoderm
H2-Aa Irf4 4.57 0.68 ectoderm
Tspan8 Irf4 4.52 0.68 ectoderm
Cd209a Ciita 5.94 0.68 ectoderm
Fcgbp Irf4 4.52 0.68 ectoderm
A630038E17Rik Irf4 4.45 0.67 ectoderm
Cd207 Ciita 5.84 0.67 ectoderm
Cd3g Irf4 4.46 0.67 ectoderm
Ctla4 Ciita 5.81 0.67 ectoderm
Tcrg-V4 Irf4 4.44 0.67 ectoderm
Cd209b Irf4 4.42 0.67 ectoderm
Cd247 Irf4 4.30 0.66 ectoderm
Pyy Irf4 4.38 0.66 ectoderm
1100001G20Rik Irf4 4.31 0.66 ectoderm
H2-Ab1 Ciita 7.66 0.66 all
Ifitm6 Irf4 4.35 0.66 ectoderm
Esr1 Irf4 4.22 0.65 ectoderm
Ffar2 Ciita 5.53 0.65 ectoderm
Itgae Irf4 4.27 0.65 ectoderm
Ffar2 Irf4 4.21 0.65 ectoderm
Defb6 Irf4 4.20 0.65 ectoderm
Ctsw Irf4 4.29 0.65 ectoderm
H2-Aa Ciita 7.45 0.65 all
Nkg7 Ciita 5.26 0.64 ectoderm
6030439D06Rik Irf4 4.17 0.64 ectoderm
Upb1 Irf4 4.12 0.64 ectoderm
Slco2b1 Irf4 4.11 0.64 ectoderm
Clec2d Irf4 4.09 0.64 ectoderm
Icos Ciita 5.09 0.63 ectoderm
Ces1d Irf4 4.02 0.63 ectoderm
Adrb2 Irf4 4.05 0.63 ectoderm
Pyy Ciita 5.10 0.63 ectoderm
Emr4 Ciita 5.05 0.62 ectoderm
Cd74 Ciita 6.88 0.62 all
Klrb1b Ciita 4.97 0.62 ectoderm
Crygn Ciita 4.84 0.61 ectoderm
Tspan8 Ciita 4.85 0.61 ectoderm
Il18r1 Ciita 4.74 0.60 ectoderm
Cd3g Ciita 4.72 0.60 ectoderm
Xcl1 Ciita 4.72 0.60 ectoderm
Alox12e Ciita 4.75 0.60 ectoderm
Cd7 Ciita 4.80 0.60 ectoderm
Cxcr6 Ciita 4.71 0.60 ectoderm
Akr1cl Ciita 4.73 0.60 ectoderm
Ccl22 Ciita 4.72 0.60 ectoderm
Itgae Ciita 4.62 0.59 ectoderm
Klrd1 Ciita 4.59 0.59 ectoderm
Cd209b Ciita 4.63 0.59 ectoderm
Hepacam2 Ciita 4.57 0.59 ectoderm
Slc36a2 Ciita 4.67 0.59 ectoderm
Gzmc Ciita 4.46 0.58 ectoderm
Cd209f Ciita 4.42 0.58 ectoderm
Fcgbp Ciita 4.52 0.58 ectoderm
Cd247 Ciita 4.47 0.58 ectoderm
A630038E17Rik Ciita 4.41 0.57 ectoderm
2310010M20Rik Ciita 4.36 0.57 ectoderm
Ear2 Ciita 4.38 0.57 ectoderm
Cd2 Ciita 5.84 0.57 all
Tcrg-V4 Ciita 4.40 0.57 ectoderm
Aqp7 Ciita 4.26 0.56 ectoderm
Ces1d Ciita 4.17 0.56 ectoderm
Rgs18 Ciita 4.27 0.56 ectoderm
D18Ertd232e Ciita 4.15 0.55 ectoderm
Meiob Ciita 4.08 0.55 ectoderm
1100001G20Rik Ciita 4.13 0.55 ectoderm
Clec2d Ciita 4.06 0.55 ectoderm
Klrb1a Ciita 4.09 0.55 ectoderm
Gpr171 Ciita 4.81 0.51 all
Kmo Ciita 4.42 0.48 all
1100001G20Rik Esr1 4.09 0.40 all
Ywhae Ciita 4.73 -0.60 ectoderm